By Airplane from Clark Airport direct flight with Sunlight Air to Tablas's own airport. Then take a minivan or jeepney to Santa Fe.
By Airplane from Manila to Caticlan's Airport (Panay Island), 30 flights every day. Then take the Bangka boat from Tabon's baybay port to Santa Fe (Tablas Island).
Take an aircon bus from PITX Manila, 2 hours to Batangas Port, then take the RORO overnight ferry (aircon cabins or bunks available) to Odiongan (Tablas Island), then aircon van for 1.5 hours to Tablas Pro Scuba
Ferry line options are 2GO, Montenegro Lines and Starlite.
See links below
Bangka boat to Santa-Fe (Tablas Island) 1 hour up to 90 min travel over sea from Caticlan. Time varies, but generally leaves Caticlan at 9AM-10AM. Book onsite at the jetty port reclamation area. First come first serve basis.